APH1B

Across TCGA cell cohorts, APH1B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,990 significant associations in total. BONE shows the largest number of these associations.

The most reproducible APH1B-associated GO terms across cancer lineages are Golgi vesicle transport, Regulation of corticotropin secretion, and Positive regulation of corticotropin secretion. Each is linked with APH1B in more than 10 cancer types. Because this analysis shows association rather than direction, both APH1B-to-partner and partner-to-APH1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi vesicle transport grouped by APH1B-low versus APH1B-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (APH1B→partner) and Y-score (partner→APH1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Golgi vesicle transport →	+0.052	+1.245	.001	.001	3	11
LUNG_NSCLC_LUSC	Regulation of corticotropin secretion →	+1.219	+1.250	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Positive regulation of corticotropin secretion →	+1.638	+1.921	<.001	<.001	3	10
STOMACH	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.072	+1.751	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Vesicle fusion →	+0.058	+0.947	.005	.004	3	9
BONE	Collagen biosynthetic process →	+0.261	+1.109	<.001	.005	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,990 associations by consensus.

Golgi vesicle transport by APH1B expression — STOMACH

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