APH1A

Across TCGA patient cohorts, APH1A RNA expression is significantly associated with the RNA expression of many other genes, with 18,771 significant associations in total. ACC shows the largest number of these associations.

The most reproducible APH1A-associated genes across cancer lineages are ISG20L2, SETDB1, and PIP5K1A. Each is linked with APH1A in more than 32 cancer types. Because this analysis shows association rather than direction, both APH1A-to-partner and partner-to-APH1A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, APH1A versus ISG20L2 in ACC, with a Pearson correlation of 0.86.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (APH1A→partner) and Y-score (partner→APH1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	ISG20L2 →	+1.256	+1.249	<.001	<.001	3	33
ACC	SETDB1 →	+1.122	+1.275	<.001	<.001	3	33
CHOL	PIP5K1A →	+1.413	+1.062	<.001	<.001	3	33
ACC	ZNF687 →	+1.302	+1.290	<.001	<.001	3	33
ACC	TARS2 →	+0.994	+1.135	<.001	<.001	3	33
ACC	PI4KB →	+1.381	+1.356	<.001	<.001	3	33

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,771 associations by consensus.

APH1A vs ISG20L2 — ACC

Explore this scatter interactively →