APBB1IP

Across TCGA pan-cancer cohorts, APBB1IP Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated APBB1IP data layer compared with 26 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher APBB1IP Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated APBB1IP expression acts as an unfavorable survival marker, although some lineages such as UCEC and LUSC show a favorable association.

OV, UCEC, and LUSC are the cancer types where APBB1IP Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	OS	Median	II,III,IV	0.289	0.692	.020	18	view →
UCEC	DFS	Median	II,III,IV	1.000	0.438	.016	18	view →
LUSC	DFS	Median	All	0.944	0.748	.015	11	view →
SKCM	DFS	Median	III,IV	0.178	0.559	.013	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

APBB1IP–OV (OS)

Open the OV breakdown →