APBB1IP

Across TCGA pan-cancer cohorts, APBB1IP mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated APBB1IP data layer compared with 26 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher APBB1IP mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated APBB1IP expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

COAD, LUAD, and PDAC are the cancer types where APBB1IP mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Quartile	II,III,IV	0.844	1.000	.022	36	view →
LUAD	DFS	Tertile	All	0.847	0.515	.002	14	view →
PDAC	OS	Median	III,IV	0.326	0.829	.004	11	view →
CCRCC	OS	Median	All	0.911	1.000	.023	2	view →
HNSC	DFS	Median	II,III,IV	0.906	0.983	.029	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

APBB1IP–COAD (DFS)

Open the COAD breakdown →