APBB1IP

Across TCGA patient cohorts, APBB1IP protein abundance is significantly associated with the RNA expression of many other genes, with 20,110 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible APBB1IP-associated genes across cancer lineages are CYTH4, IL2RB, and SIRPB1. Each is linked with APBB1IP in more than 9 cancer types. Because this analysis shows association rather than direction, both APBB1IP-to-partner and partner-to-APBB1IP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, APBB1IP versus CYTH4 in GBM, with a Pearson correlation of 0.82.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (APBB1IP→partner) and Y-score (partner→APBB1IP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CYTH4 →	+1.198	+0.762	<.001	<.001	3	10
OV	IL2RB →	+1.558	+0.764	<.001	<.001	3	10
HNSC	SIRPB1 →	+0.642	+0.474	<.001	<.001	3	10
GBM	HCK →	+1.306	+0.798	<.001	<.001	3	10
OV	TNFSF13B →	+1.067	+0.539	<.001	<.001	3	10
GBM	LILRB1 →	+1.185	+0.789	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,110 associations by consensus.

APBB1IP vs CYTH4 — GBM

Explore this scatter interactively →