APBB1IP

Across TCGA patient cohorts, APBB1IP mutation is significantly associated with the RNA expression of many other genes, with 1,503 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible APBB1IP-associated genes across cancer lineages are RNU2-17P, MSANTD3, and CDADC1. Each is linked with APBB1IP in more than 2 cancer types. Because this analysis shows association rather than direction, both APBB1IP-to-partner and partner-to-APBB1IP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU2-17P grouped by APBB1IP-low versus APBB1IP-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (APBB1IP→partner) and Y-score (partner→APBB1IP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNU2-17P →	+0.417	+2.388	<.001	.001	3	3
UCEC	MSANTD3 →	+0.551	+2.180	<.001	.002	3	3
SKCM	CDADC1 →	+0.335	+1.778	.006	.007	3	3
UCEC	CARS1 →	+0.464	+1.776	<.001	.008	3	3
UCEC	C9orf78 →	+0.326	+2.931	.004	<.001	3	3
UCEC	NDUFAF1 →	+0.481	+3.332	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,503 associations by consensus.

RNU2-17P by APBB1IP expression — LUSC

Explore this box plot interactively →