APBB1IP

Across TCGA cell cohorts, APBB1IP mutation is significantly associated with the RNA expression of many other genes, with 273 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible APBB1IP-associated genes across cancer lineages are OR10K2, CD300LF, and OR6C70. Each is linked with APBB1IP in more than 1 cancer types. Because this analysis shows association rather than direction, both APBB1IP-to-partner and partner-to-APBB1IP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10K2 grouped by APBB1IP-low versus APBB1IP-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (APBB1IP→partner) and Y-score (partner→APBB1IP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	OR10K2 →	+0.031	+3.781	<.001	.009	3	2
SKIN	CD300LF →	+0.620	+3.459	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR6C70 →	+0.292	+4.681	<.001	.003	3	1
LUNG_NSCLC_LUAD	C3orf84 →	+0.016	+4.681	<.001	.003	3	1
LARGE_INTESTINE	CBY1 →	+0.645	+3.299	.001	.004	3	1
LARGE_INTESTINE	MCM5 →	+0.696	+3.064	.008	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 273 associations by consensus.

OR10K2 by APBB1IP expression — BREAST

Explore this box plot interactively →