APBA1

Across TCGA patient cohorts, APBA1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,175 significant associations in total. GBM shows the largest number of these associations.

The most reproducible APBA1-associated genes across cancer lineages are LMOD1, KANK2, and DNM3OS. Each is linked with APBA1 in more than 5 cancer types. Because this analysis shows association rather than direction, both APBA1-to-partner and partner-to-APBA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, APBA1 versus LMOD1 in UCEC, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (APBA1→partner) and Y-score (partner→APBA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LMOD1 →	+1.585	+0.484	<.001	<.001	3	5
UCEC	KANK2 →	+0.741	+0.476	<.001	<.001	3	5
UCEC	DNM3OS →	+0.988	+0.435	<.001	<.001	3	5
CCRCC	AQP1 →	+1.562	+0.465	<.001	<.001	3	5
CCRCC	IRAG1 →	+0.839	+0.393	.003	.003	2	6
UCEC	TIMP3 →	+1.460	+0.441	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,175 associations by consensus.

APBA1 vs LMOD1 — UCEC

Explore this scatter interactively →