APBA1

Across TCGA patient cohorts, APBA1 protein abundance is significantly associated with the protein abundance of many other proteins, with 24,926 significant associations in total. GBM shows the largest number of these associations.

The most reproducible APBA1-associated proteins across cancer lineages are SEPTIN4, SEPTIN7, and APBA1_S285. Each is linked with APBA1 in more than 5 cancer types. Because this analysis shows association rather than direction, both APBA1-to-partner and partner-to-APBA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, APBA1 versus SEPTIN4 in GBM, with a Pearson correlation of 0.57.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (APBA1→partner) and Y-score (partner→APBA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SEPTIN4 →	+0.698	+0.407	<.001	<.001	3	6
BRCA	SEPTIN7 →	+0.318	+0.473	<.001	<.001	3	6
GBM	APBA1_S285 →	+0.649	+0.542	<.001	<.001	3	6
GBM	PLOD2 →	-1.275	-0.503	<.001	<.001	3	5
UCEC	SEPTIN11 →	+0.494	+0.576	<.001	<.001	3	5
GBM	SEPTIN4_S325 →	+0.632	+0.380	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 24,926 associations by consensus.

APBA1 vs SEPTIN4 — GBM

Explore this scatter interactively →