APBA1

Across TCGA cell cohorts, APBA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,971 significant associations in total. BONE shows the largest number of these associations.

The most reproducible APBA1-associated GO terms across cancer lineages are Endosomal transport, Schwann cell differentiation, and Negative regulation of myoblast fusion. Each is linked with APBA1 in more than 9 cancer types. Because this analysis shows association rather than direction, both APBA1-to-partner and partner-to-APBA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal transport grouped by APBA1-low versus APBA1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (APBA1→partner) and Y-score (partner→APBA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.063	+0.863	<.001	<.001	3	10
URINARY_TRACT	Schwann cell differentiation →	+0.129	+1.088	<.001	.001	3	10
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.144	+0.950	<.001	<.001	3	9
OESOPHAGUS	Positive regulation of cytoplasmic translation →	+0.123	+1.643	.004	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.142	+0.944	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Regulation of syncytium formation by plasma membrane fusion →	+0.118	+0.963	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,971 associations by consensus.

Endosomal transport by APBA1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →