AP5Z1

Across TCGA patient cohorts, AP5Z1 RNA expression is significantly associated with the mutation status of many other genes, with 9,180 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AP5Z1-associated genes across cancer lineages are TP53, EGFR, and TTN. Each is linked with AP5Z1 in more than 7 cancer types. Because this analysis shows association rather than direction, both AP5Z1-to-partner and partner-to-AP5Z1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TP53 grouped by AP5Z1-low versus AP5Z1-high in LIHC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AP5Z1→partner) and Y-score (partner→AP5Z1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	TP53 →	+1.767	+0.591	<.001	<.001	3	8
LGG	EGFR →	+2.671	+0.452	<.001	<.001	3	3
LGG	TTN →	+1.410	+0.210	.007	.003	2	4
UCEC	DSG3 →	+1.705	+0.320	<.001	<.001	3	3
CESC	HECW1 →	+3.199	+0.353	.009	.008	2	4
STAD	FAT4 →	-1.836	-0.281	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,180 associations by consensus.

TP53 by AP5Z1 expression — LIHC

Explore this box plot interactively →