AP5Z1

Across TCGA patient cohorts, AP5Z1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,331 significant associations in total. GBM shows the largest number of these associations.

The most reproducible AP5Z1-associated genes across cancer lineages are CD84, NCKAP1L, and MYO1F. Each is linked with AP5Z1 in more than 6 cancer types. Because this analysis shows association rather than direction, both AP5Z1-to-partner and partner-to-AP5Z1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AP5Z1 versus CD84 in BRCA, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AP5Z1→partner) and Y-score (partner→AP5Z1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CD84 →	+0.867	+0.192	<.001	<.001	3	7
BRCA	NCKAP1L →	+0.820	+0.183	<.001	<.001	3	6
BRCA	MYO1F →	+0.840	+0.206	<.001	<.001	3	6
BRCA	LAIR1 →	+0.853	+0.238	<.001	<.001	3	6
BRCA	CD33 →	+0.541	+0.182	<.001	<.001	3	5
LSCC	PIK3CG →	+0.756	+0.188	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,331 associations by consensus.

AP5Z1 vs CD84 — BRCA

Explore this scatter interactively →