AP4S1

Across TCGA cell cohorts, AP4S1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,653 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible AP4S1-associated GO terms across cancer lineages are Vesicle tethering to Golgi, Protein localization to condensed chromosome, and Double-strand break repair via homologous recombination. Each is linked with AP4S1 in more than 13 cancer types. Because this analysis shows association rather than direction, both AP4S1-to-partner and partner-to-AP4S1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle tethering to Golgi grouped by AP4S1-low versus AP4S1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AP4S1→partner) and Y-score (partner→AP4S1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Vesicle tethering to Golgi →	+0.151	+1.178	<.001	.006	3	14
OESOPHAGUS	Protein localization to condensed chromosome →	+0.145	+0.906	.009	.006	3	12
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair via homologous recombination →	+0.086	+1.236	.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Recombinational repair →	+0.085	+1.244	.002	<.001	3	11
STOMACH	Monoubiquitinated protein deubiquitination →	+0.150	+1.377	.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair →	+0.068	+1.052	.002	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,653 associations by consensus.

Vesicle tethering to Golgi by AP4S1 expression — STOMACH

Explore this box plot interactively →