Across TCGA patient cohorts, AP4M1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,826 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible AP4M1-associated genes across cancer lineages are GAB1, PLCE1, and IGSF11. Each is linked with AP4M1 in more than 2 cancer types. Because this analysis shows association rather than direction, both AP4M1-to-partner and partner-to-AP4M1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AP4M1→partner) and Y-score (partner→AP4M1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GAB1 →	-0.622	-0.189	<.001	.001	3	3
PDAC	PLCE1 →	-0.446	-0.262	<.001	<.001	3	3
LSCC	IGSF11 →	-0.830	-0.112	.002	.002	3	3
GBM	HMGCLL1 →	-0.676	-0.214	.003	.001	3	3
HNSC	NR3C2 →	-0.838	-0.257	<.001	<.001	3	3
CCRCC	SLC16A9 →	-1.188	-0.113	<.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,826 associations by consensus.

Exploration

AP4M1 survival (RNA) · tumor vs normal (RNA) · all AP4M1 data types