Across TCGA cell cohorts, AP4M1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,301 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AP4M1-associated GO terms across cancer lineages are Pre-mRNA catabolic process, Positive regulation of isotype switching to IgG isotypes, and Regulation of G0 to G1 transition. Each is linked with AP4M1 in more than 17 cancer types. Because this analysis shows association rather than direction, both AP4M1-to-partner and partner-to-AP4M1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AP4M1→partner) and Y-score (partner→AP4M1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Pre-mRNA catabolic process →	+0.145	+0.977	.001	<.001	3	18
BONE	Positive regulation of isotype switching to IgG isotypes →	+0.140	+0.976	<.001	<.001	3	12
BLOOD_Lymphoma	Regulation of G0 to G1 transition →	+0.107	+0.684	<.001	<.001	3	12
CNS	Golgi to lysosome transport →	+0.100	+0.744	<.001	<.001	3	11
BONE	Regulation of double-strand break repair via homologous recombination →	+0.089	+1.332	<.001	<.001	3	10
BONE	Positive regulation of double-strand break repair via homologous recombination →	+0.084	+0.981	.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,301 associations by consensus.

Exploration

AP4M1 survival (RNA) · tumor vs normal (RNA) · all AP4M1 data types