AP3S1

Across TCGA patient cohorts, AP3S1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,386 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible AP3S1-associated proteins across cancer lineages are YTHDC2, P4HA2, and PPIP5K2. Each is linked with AP3S1 in more than 6 cancer types. Because this analysis shows association rather than direction, both AP3S1-to-partner and partner-to-AP3S1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AP3S1 versus YTHDC2 in OV, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AP3S1→partner) and Y-score (partner→AP3S1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	YTHDC2 →	+0.296	+0.556	.004	.006	2	7
PDAC	P4HA2 →	+0.554	+0.433	<.001	<.001	3	5
COAD	PPIP5K2 →	+0.247	+0.478	.001	.008	3	5
OV	CHD1 →	+0.323	+0.481	.002	.002	3	4
PDAC	FSCN1_S39 →	+0.660	+0.393	<.001	<.001	3	4
PDAC	TBC1D2 →	+0.358	+0.576	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,386 associations by consensus.

AP3S1 vs YTHDC2 — OV

Explore this scatter interactively →