AP3D1

Across TCGA patient cohorts, AP3D1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,412 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AP3D1-associated genes across cancer lineages are RND2, MPP2, and AP3B1. Each is linked with AP3D1 in more than 3 cancer types. Because this analysis shows association rather than direction, both AP3D1-to-partner and partner-to-AP3D1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AP3D1 versus RND2 in LSCC, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AP3D1→partner) and Y-score (partner→AP3D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RND2 →	-0.731	-0.094	<.001	<.001	3	4
LSCC	MPP2 →	-0.692	-0.100	<.001	.002	3	4
BRCA	AP3B1 →	+0.503	+0.252	<.001	<.001	3	4
COAD	GLRX →	+0.734	+0.135	.001	.001	3	4
BRCA	CCDC125 →	+0.644	+0.173	<.001	<.001	3	4
HNSC	MYL6B →	-0.699	-0.110	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,412 associations by consensus.

AP3D1 vs RND2 — LSCC

Explore this scatter interactively →