AP3B1

Across TCGA patient cohorts, AP3B1 mutation is significantly associated with the RNA expression of many other genes, with 3,153 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AP3B1-associated genes across cancer lineages are OR13C3, PYY3, and RNU6-1313P. Each is linked with AP3B1 in more than 2 cancer types. Because this analysis shows association rather than direction, both AP3B1-to-partner and partner-to-AP3B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR13C3 grouped by AP3B1-low versus AP3B1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AP3B1→partner) and Y-score (partner→AP3B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	OR13C3 →	+0.020	+4.569	<.001	.005	3	3
LUSC	PYY3 →	+0.133	+4.099	<.001	.008	3	3
HNSC	RNU6-1313P →	+0.257	+4.526	<.001	.007	3	3
LUAD	TSPY8 →	+0.053	+5.739	<.001	.001	3	3
UCEC	RNA5SP413 →	+0.897	+1.585	<.001	.003	3	3
UCEC	ABHD3 →	+0.618	+3.343	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,153 associations by consensus.

OR13C3 by AP3B1 expression — CESC

Explore this box plot interactively →