AP2S1

Across TCGA patient cohorts, AP2S1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,027 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible AP2S1-associated proteins across cancer lineages are PLAU, CDKN1B, and ITGA5. Each is linked with AP2S1 in more than 5 cancer types. Because this analysis shows association rather than direction, both AP2S1-to-partner and partner-to-AP2S1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AP2S1 versus PLAU in CCRCC, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AP2S1→partner) and Y-score (partner→AP2S1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	PLAU →	+1.216	+0.408	.001	<.001	3	6
GBM	CDKN1B →	-0.413	-0.367	.001	<.001	3	6
PDAC	ITGA5 →	+0.451	+0.281	<.001	<.001	3	6
GBM	MMP14 →	+0.580	+0.393	<.001	<.001	3	5
HNSC	MYEF2_S17 →	-0.746	-0.608	.003	.008	3	5
LSCC	TMTC3 →	+0.379	+0.350	.004	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,027 associations by consensus.

AP2S1 vs PLAU — CCRCC

Explore this scatter interactively →