AP2S1

Across TCGA patient cohorts, AP2S1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,824 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AP2S1-associated genes across cancer lineages are TLL1, DKC1, and MMP19. Each is linked with AP2S1 in more than 4 cancer types. Because this analysis shows association rather than direction, both AP2S1-to-partner and partner-to-AP2S1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AP2S1 versus TLL1 in OV, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AP2S1→partner) and Y-score (partner→AP2S1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TLL1 →	+0.821	+0.225	<.001	<.001	3	5
LSCC	DKC1 →	-0.633	-0.154	<.001	<.001	3	5
LSCC	MMP19 →	+1.159	+0.208	<.001	<.001	3	4
OV	SFRP2 →	+2.700	+0.248	.003	.001	3	4
HNSC	VEGFC →	+0.847	+0.179	.003	.001	3	4
BRCA	PRICKLE2 →	+0.732	+0.207	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,824 associations by consensus.

AP2S1 vs TLL1 — OV

Explore this scatter interactively →