AP2M1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, AP2M1 protein abundance is significantly associated with the RNA expression of many other genes, with 17,632 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AP2M1-associated genes across cancer lineages are ZCCHC24, RASGRF2, and GLT8D2. Each is linked with AP2M1 in more than 8 cancer types. Because this analysis shows association rather than direction, both AP2M1-to-partner and partner-to-AP2M1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AP2M1 versus ZCCHC24 in OV, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AP2M1→partner) and Y-score (partner→AP2M1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVZCCHC24 →+0.897+0.242<.001<.00139
OVRASGRF2 →+0.815+0.227<.001.00438
OVGLT8D2 →+1.870+0.339<.001<.00138
UCECTSHZ3 →+1.030+0.163<.001<.00138
OVTIMP3 →+1.529+0.261<.001<.00137
OVCCN4 →+1.939+0.304<.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 17,632 associations by consensus.

AP2M1 vs ZCCHC24 — OV

Per-sample scatter of AP2M1 vs ZCCHC24 in OV (Pearson r = 0.51).

Explore this scatter interactively →

Exploration