AP1S3

Across TCGA patient cohorts, AP1S3 protein abundance is significantly associated with the RNA expression of many other genes, with 5,966 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AP1S3-associated genes across cancer lineages are ITPRID2, MALL, and ACSL3. Each is linked with AP1S3 in more than 4 cancer types. Because this analysis shows association rather than direction, both AP1S3-to-partner and partner-to-AP1S3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AP1S3 versus ITPRID2 in BRCA, with a Pearson correlation of 0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AP1S3→partner) and Y-score (partner→AP1S3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ITPRID2 →	+1.083	+0.427	<.001	.005	3	5
HNSC	MALL →	+0.941	+0.294	.002	.009	3	4
COAD	ACSL3 →	+0.626	+0.780	<.001	.001	3	3
BRCA	VASH2 →	-0.806	-0.594	.002	.001	3	3
LSCC	ADGRF4 →	+1.234	+0.486	<.001	.001	3	3
BRCA	FBXO36 →	+0.614	+0.442	.006	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,966 associations by consensus.

AP1S3 vs ITPRID2 — BRCA

Explore this scatter interactively →