AP1S1

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, AP1S1 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AP1S1-associated genes across cancer lineages are Pericytes. Each is linked with AP1S1 in more than 1 cancer types. Because this analysis shows association rather than direction, both AP1S1-to-partner and partner-to-AP1S1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pericytes grouped by AP1S1-low versus AP1S1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AP1S1→partner) and Y-score (partner→AP1S1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECPericytes →+0.036+2.528.040.02531
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Pericytes by AP1S1 expression — UCEC

Box plot of Pericytes in AP1S1-low vs AP1S1-high samples in UCEC.

Explore this box plot interactively →

Exploration