AOC3

Across TCGA patient cohorts, AOC3 RNA expression is significantly associated with the protein abundance of many other proteins, with 26,191 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AOC3-associated proteins across cancer lineages are ILK, ISLR, and ITGA7. Each is linked with AOC3 in more than 9 cancer types. Because this analysis shows association rather than direction, both AOC3-to-partner and partner-to-AOC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AOC3 versus ILK in UCEC, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AOC3→partner) and Y-score (partner→AOC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ILK →	+0.533	+0.892	<.001	<.001	3	10
BRCA	ISLR →	+0.749	+1.344	<.001	<.001	3	10
BRCA	ITGA7 →	+0.951	+1.511	<.001	<.001	3	10
BRCA	KANK2_S375 →	+0.656	+1.440	<.001	<.001	3	10
BRCA	LUM →	+1.058	+1.444	<.001	<.001	3	10
BRCA	MSRB3 →	+0.943	+1.531	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 26,191 associations by consensus.

AOC3 vs ILK — UCEC

Explore this scatter interactively →