AOC1

Across TCGA cell cohorts, AOC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,920 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible AOC1-associated GO terms across cancer lineages are Regulation of myoblast fusion, Positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, and Negative regulation of myoblast fusion. Each is linked with AOC1 in more than 7 cancer types. Because this analysis shows association rather than direction, both AOC1-to-partner and partner-to-AOC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by AOC1-low versus AOC1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AOC1→partner) and Y-score (partner→AOC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of myoblast fusion →	+0.108	+0.072	<.001	<.001	3	8
STOMACH	Positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay →	+0.178	+2.657	<.001	<.001	3	8
BONE	Negative regulation of myoblast fusion →	+0.079	+0.049	<.001	<.001	3	7
STOMACH	Telomere assembly →	-0.098	-1.840	<.001	.005	3	7
STOMACH	Negative regulation of mast cell degranulation →	+1.646	+2.847	<.001	<.001	3	7
LUNG_NSCLC_LUAD	Regulation of tolerance induction dependent upon immune response →	+0.993	+1.436	.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,920 associations by consensus.

Regulation of myoblast fusion by AOC1 expression — BONE

Explore this box plot interactively →