ANXA8L1

Across TCGA pan-cancer cohorts, ANXA8L1 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated ANXA8L1 data layer compared with 22 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher ANXA8L1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ANXA8L1 expression acts as an unfavorable survival marker.

PAAD and COAD are the cancer types where ANXA8L1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PAAD	OS	Median	All	0.140	0.590	<.001	24	view →
COAD	OS	Median	III,IV	0.056	0.783	<.001	24	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

ANXA8L1–PAAD (OS)

Open the PAAD breakdown →