ANXA8L1

Across TCGA patient cohorts, ANXA8L1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,541 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ANXA8L1-associated genes across cancer lineages are ANXA8, ADGRF4, and RNASE7. Each is linked with ANXA8L1 in more than 5 cancer types. Because this analysis shows association rather than direction, both ANXA8L1-to-partner and partner-to-ANXA8L1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANXA8L1 versus ANXA8 in LSCC, with a Pearson correlation of 0.85.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANXA8L1→partner) and Y-score (partner→ANXA8L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ANXA8 →	+2.289	+1.642	<.001	<.001	3	6
LSCC	ADGRF4 →	+1.102	+0.931	<.001	<.001	3	5
LSCC	RNASE7 →	+1.564	+0.901	<.001	<.001	3	5
UCEC	GNA15 →	+0.966	+1.940	.005	.002	3	5
UCEC	TMEM40 →	+1.281	+1.991	<.001	<.001	3	5
LSCC	KRT5 →	+3.005	+1.144	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,541 associations by consensus.

ANXA8L1 vs ANXA8 — LSCC

Explore this scatter interactively →