ANXA8L1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ANXA8L1 mutation is significantly associated with the RNA expression of many other genes, with 1,371 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANXA8L1-associated genes across cancer lineages are RN7SKP261, MIR6802, and MIR7843. Each is linked with ANXA8L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANXA8L1-to-partner and partner-to-ANXA8L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP261 grouped by ANXA8L1-low versus ANXA8L1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANXA8L1→partner) and Y-score (partner→ANXA8L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRN7SKP261 →+0.448+2.903<.001.00132
COADMIR6802 →+0.522+4.962<.001.00332
CESCMIR7843 →+0.480+5.418<.001.00532
COADTRIM48 →+0.084+4.807.007.00431
UCECC3orf38 →+0.560+3.459.006.00531
UCECRCC2 →+0.524+3.364.008.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,371 associations by consensus.

RN7SKP261 by ANXA8L1 expression — UCEC

Box plot of RN7SKP261 in ANXA8L1-low vs ANXA8L1-high samples in UCEC.

Explore this box plot interactively →

Exploration