ANXA8L1

Across TCGA patient cohorts, ANXA8L1 mutation is significantly associated with the total protein of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANXA8L1-associated genes across cancer lineages are JNK_pT183_Y185, PCNA, and ASNS. Each is linked with ANXA8L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANXA8L1-to-partner and partner-to-ANXA8L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JNK_pT183_Y185 grouped by ANXA8L1-low versus ANXA8L1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANXA8L1→partner) and Y-score (partner→ANXA8L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK_pT183_Y185 →	-0.232	-2.986	.017	.037	3	1
UCEC	PCNA →	+0.280	+3.000	.025	.037	3	1
UCEC	ASNS →	+0.543	+3.000	.009	.037	3	1
UCEC	Ku80 →	+0.503	+3.013	<.001	.019	2	1
UCEC	Rictor_pT1135 →	-0.116	-3.000	.049	.037	2	1
UCEC	Lck →	-0.308	-3.000	.007	.037	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

JNK_pT183_Y185 by ANXA8L1 expression — UCEC

Explore this box plot interactively →