ANXA8L1

Across TCGA cell cohorts, ANXA8L1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,733 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ANXA8L1-associated GO terms across cancer lineages are Regulation of extrinsic apoptotic signaling pathway, Negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway, and Positive regulation of plasma membrane repair. Each is linked with ANXA8L1 in more than 11 cancer types. Because this analysis shows association rather than direction, both ANXA8L1-to-partner and partner-to-ANXA8L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of extrinsic apoptotic signaling pathway grouped by ANXA8L1-low versus ANXA8L1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ANXA8L1→partner) and Y-score (partner→ANXA8L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of extrinsic apoptotic signaling pathway →	+0.088	+3.744	<.001	.001	3	12
PANCREAS	Negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway →	+0.134	+3.906	<.001	<.001	3	12
STOMACH	Positive regulation of plasma membrane repair →	+0.170	+3.939	.001	<.001	3	12
URINARY_TRACT	Plasma membrane organization →	+0.121	+5.463	<.001	<.001	3	11
LARGE_INTESTINE	Positive regulation of neuromuscular junction development →	+0.138	+1.583	<.001	<.001	3	11
BREAST	Regulation of cytokine-mediated signaling pathway →	+0.082	+3.639	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,733 associations by consensus.

Regulation of extrinsic apoptotic signaling pathway by ANXA8L1 expression — STOMACH

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