ANXA8

Across TCGA patient cohorts, ANXA8 protein abundance is significantly associated with the RNA expression of many other genes, with 9,561 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ANXA8-associated genes across cancer lineages are ANXA8L1, KRT6A, and MYEF2. Each is linked with ANXA8 in more than 5 cancer types. Because this analysis shows association rather than direction, both ANXA8-to-partner and partner-to-ANXA8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANXA8 versus ANXA8L1 in BRCA, with a Pearson correlation of 0.72.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANXA8→partner) and Y-score (partner→ANXA8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ANXA8L1 →	+2.189	+1.719	<.001	<.001	3	6
LSCC	KRT6A →	+3.139	+1.437	<.001	<.001	3	5
LSCC	MYEF2 →	-0.852	-1.119	<.001	<.001	3	4
UCEC	FAM83A →	+2.001	+1.456	.001	.001	3	4
UCEC	MAGI1 →	-0.676	-1.210	.001	.001	3	4
UCEC	RNASE7 →	+2.176	+1.551	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,561 associations by consensus.

ANXA8 vs ANXA8L1 — BRCA

Explore this scatter interactively →