ANXA5

Across TCGA cell cohorts, ANXA5 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,681 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ANXA5-associated GO terms across cancer lineages are Elastin metabolic process, Regulation of plasminogen activation, and Positive regulation of cell-substrate junction organization. Each is linked with ANXA5 in more than 13 cancer types. Because this analysis shows association rather than direction, both ANXA5-to-partner and partner-to-ANXA5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Elastin metabolic process grouped by ANXA5-low versus ANXA5-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ANXA5→partner) and Y-score (partner→ANXA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Elastin metabolic process →	+0.304	+2.412	<.001	<.001	3	14
BONE	Regulation of plasminogen activation →	+0.329	+2.768	<.001	<.001	3	12
BONE	Positive regulation of cell-substrate junction organization →	+0.182	+1.894	<.001	<.001	3	12
BONE	Negative regulation of Rho protein signal transduction →	+0.235	+2.497	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Establishment of epithelial cell apical/basal polarity →	+0.225	+1.382	<.001	<.001	3	12
BONE	Regulation of transmembrane receptor protein serine/threonine kinase signaling pathway →	+0.079	+2.311	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,681 associations by consensus.

Elastin metabolic process by ANXA5 expression — BONE

Explore this box plot interactively →