ANXA11

Across TCGA cell cohorts, ANXA11 mutation is significantly associated with the mutation status of many other genes, with 2,345 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANXA11-associated genes across cancer lineages are XAB2, USHBP1, and EPHB6. Each is linked with ANXA11 in more than 2 cancer types. Because this analysis shows association rather than direction, both ANXA11-to-partner and partner-to-ANXA11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, XAB2 grouped by ANXA11-low versus ANXA11-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANXA11→partner) and Y-score (partner→ANXA11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	XAB2 →	+3.063	+3.498	.006	.006	1	3
BLOOD_Leukemia	USHBP1 →	+3.548	+3.845	.003	.003	1	3
BLOOD_Leukemia	EPHB6 →	+2.478	+3.544	.004	.004	1	3
BLOOD_Leukemia	CLK1 →	+5.285	+4.321	.005	.005	1	3
BLOOD_Leukemia	AP3D1 →	+2.870	+3.347	.009	.009	1	3
SKIN	EHMT2 →	+3.655	+4.906	.001	.001	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,345 associations by consensus.

XAB2 by ANXA11 expression — BLOOD_Leukemia

Explore this box plot interactively →