ANXA10

Across TCGA patient cohorts, ANXA10 mutation is significantly associated with the total protein of many other genes, with 32 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANXA10-associated genes across cancer lineages are ACVRL1, P-Cadherin, and IRS1. Each is linked with ANXA10 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANXA10-to-partner and partner-to-ANXA10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACVRL1 grouped by ANXA10-low versus ANXA10-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANXA10→partner) and Y-score (partner→ANXA10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	ACVRL1 →	+0.119	+2.334	.041	.018	3	2
UCEC	P-Cadherin →	-0.152	-3.321	.007	.009	3	2
SKCM	IRS1 →	+0.158	+2.824	.014	.034	3	1
SKCM	PARP_cleaved →	+0.139	+1.700	.034	.043	3	1
SKCM	DJ-1 →	+0.190	+3.169	.012	.017	3	1
UCEC	eIF4E →	+0.167	+2.502	.043	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

ACVRL1 by ANXA10 expression — SKCM

Explore this box plot interactively →