ANXA10

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ANXA10 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANXA10-associated genes across cancer lineages are LCE5A, SMR3B, and OR1L1. Each is linked with ANXA10 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANXA10-to-partner and partner-to-ANXA10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LCE5A grouped by ANXA10-low versus ANXA10-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANXA10→partner) and Y-score (partner→ANXA10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUADLCE5A →+0.048+3.770.008.00831
BLOOD_LeukemiaSMR3B →+0.058+4.922<.001.00931
LARGE_INTESTINEOR1L1 →+0.029+4.415<.001.00731
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

LCE5A by ANXA10 expression — LUNG_NSCLC_LUAD

Box plot of LCE5A in ANXA10-low vs ANXA10-high samples in LUNG_NSCLC_LUAD.

Explore this box plot interactively →

Exploration