ANTXR1

Across TCGA patient cohorts, ANTXR1 mutation is significantly associated with the total protein of many other genes, with 49 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANTXR1-associated genes across cancer lineages are eEF2, JNK2, and p70-S6K_pT389. Each is linked with ANTXR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANTXR1-to-partner and partner-to-ANTXR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by ANTXR1-low versus ANTXR1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANTXR1→partner) and Y-score (partner→ANTXR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.308	+2.000	.008	.009	3	2
UCEC	JNK2 →	+0.282	+3.727	<.001	<.001	3	2
UCEC	p70-S6K_pT389 →	-0.188	-2.700	.002	.005	3	2
UCEC	TSC1 →	-0.132	-2.661	.019	.005	3	2
UCEC	beta-Catenin →	+0.430	+2.700	.009	.005	3	2
UCEC	C-Raf →	+0.131	+1.415	.005	.043	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

eEF2 by ANTXR1 expression — UCEC

Explore this box plot interactively →