ANP32E

Across TCGA patient cohorts, ANP32E mutation is significantly associated with the RNA expression of many other genes, with 2,352 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANP32E-associated genes across cancer lineages are MIR6856, LINC00251, and RNU1-82P. Each is linked with ANP32E in more than 1 cancer types. Because this analysis shows association rather than direction, both ANP32E-to-partner and partner-to-ANP32E results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6856 grouped by ANP32E-low versus ANP32E-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANP32E→partner) and Y-score (partner→ANP32E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR6856 →	+0.625	+4.313	.001	.007	3	2
BRCA	LINC00251 →	+0.053	+4.883	<.001	.006	3	2
BRCA	RNU1-82P →	+0.157	+4.971	<.001	.005	3	2
BLCA	RAB11AP1 →	+0.095	+5.251	<.001	.006	3	2
UCEC	NIPA2P4 →	+0.046	+2.106	.002	.001	3	2
BRCA	MIR6769B →	+0.370	+6.878	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,352 associations by consensus.

MIR6856 by ANP32E expression — BRCA

Explore this box plot interactively →