ANP32E

Across TCGA cell cohorts, ANP32E RNA expression is significantly associated with the go_rna of many other GO terms, with 4,623 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ANP32E-associated GO terms across cancer lineages are Chromosome segregation, Regulation of chromosome condensation, and Mitotic sister chromatid cohesion. Each is linked with ANP32E in more than 18 cancer types. Because this analysis shows association rather than direction, both ANP32E-to-partner and partner-to-ANP32E results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Chromosome segregation grouped by ANP32E-low versus ANP32E-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ANP32E→partner) and Y-score (partner→ANP32E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Chromosome segregation →	+0.131	+1.282	<.001	<.001	3	19
BONE	Regulation of chromosome condensation →	+0.195	+1.206	<.001	<.001	3	19
KIDNEY	Mitotic sister chromatid cohesion →	+0.119	+0.836	<.001	<.001	3	19
KIDNEY	Nuclear chromosome segregation →	+0.134	+1.091	<.001	<.001	3	18
SOFT_TISSUE	Regulation of microtubule-based process →	+0.063	+1.325	<.001	<.001	3	18
SKIN	Spindle elongation →	+0.219	+0.964	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,623 associations by consensus.

Chromosome segregation by ANP32E expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →