ANP32D

Across TCGA patient cohorts, ANP32D mutation is significantly associated with the total protein of many other genes, with 7 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible ANP32D-associated genes across cancer lineages are Bim, eEF2K, and Rictor. Each is linked with ANP32D in more than 1 cancer types. Because this analysis shows association rather than direction, both ANP32D-to-partner and partner-to-ANP32D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Bim grouped by ANP32D-low versus ANP32D-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANP32D→partner) and Y-score (partner→ANP32D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Bim →	-0.325	-3.000	.033	.036	3	1
SKCM	eEF2K →	-0.536	-2.982	.007	.036	3	1
SKCM	Rictor →	-0.578	-3.000	.001	.036	2	1
UCEC	MEK1 →	+0.704	+3.000	<.001	.037	1	1
UCEC	Notch1 →	+0.222	+3.000	.006	.037	1	1
UCEC	Annexin-1 →	+0.792	+3.000	.009	.037	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Bim by ANP32D expression — SKCM

Explore this box plot interactively →