ANP32D

Across TCGA cell cohorts, ANP32D RNA expression is significantly associated with the go_rna of many other GO terms, with 1,668 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ANP32D-associated GO terms across cancer lineages are mRNA alternative polyadenylation, Negative regulation of mRNA metabolic process, and Positive regulation of T-helper 17 cell lineage commitment. Each is linked with ANP32D in more than 6 cancer types. Because this analysis shows association rather than direction, both ANP32D-to-partner and partner-to-ANP32D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA alternative polyadenylation grouped by ANP32D-low versus ANP32D-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ANP32D→partner) and Y-score (partner→ANP32D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	mRNA alternative polyadenylation →	+0.055	+0.063	.001	.003	3	7
UPPER_AERODIGESTIVE_TRACT	Negative regulation of mRNA metabolic process →	+0.061	+0.089	<.001	.001	3	6
UPPER_AERODIGESTIVE_TRACT	Positive regulation of T-helper 17 cell lineage commitment →	+0.119	+0.047	.008	.005	3	6
UPPER_AERODIGESTIVE_TRACT	Regulatory ncRNA-mediated gene silencing →	+0.038	+0.054	.009	.007	3	6
BONE	Response to dehydroepiandrosterone →	+0.131	+0.053	.003	.009	3	6
BLOOD_Leukemia	Regulation of alternative mRNA splicing, via spliceosome →	+0.059	+0.029	.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,668 associations by consensus.

mRNA alternative polyadenylation by ANP32D expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →