ANP32A

Across TCGA pan-cancer cohorts, ANP32A Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated ANP32A data layer compared with 23 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher ANP32A Mutation is associated with better overall survival. In most high-consensus cancer types, elevated ANP32A expression acts as an unfavorable survival marker, although some lineages such as BLCA show a favorable association.

BLCA and UCEC are the cancer types where ANP32A Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Median	II,III,IV	1.000	0.418	.011	31	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

ANP32A–BLCA (OS)

Open the BLCA breakdown →