ANP32A

Across TCGA patient cohorts, ANP32A mutation is significantly associated with the RNA expression of many other genes, with 241 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANP32A-associated genes across cancer lineages are RNA5SP412, RNU6-1085P, and RNU6-1318P. Each is linked with ANP32A in more than 1 cancer types. Because this analysis shows association rather than direction, both ANP32A-to-partner and partner-to-ANP32A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP412 grouped by ANP32A-low versus ANP32A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANP32A→partner) and Y-score (partner→ANP32A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP412 →	+0.770	+2.481	<.001	.006	3	2
UCEC	RNU6-1085P →	+0.335	+2.599	<.001	.009	3	2
UCEC	RNU6-1318P →	+0.466	+3.358	<.001	.001	3	2
BRCA	MIR3118-3 →	+0.371	+7.471	<.001	.008	3	1
READ	OR5AN1 →	+0.093	+7.276	<.001	<.001	3	1
READ	UBE2Q2P12 →	+0.393	+6.681	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 241 associations by consensus.

RNA5SP412 by ANP32A expression — UCEC

Explore this box plot interactively →