ANP32A

Across TCGA patient cohorts, ANP32A mutation is significantly associated with the total protein of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANP32A-associated genes across cancer lineages are FoxM1, MSH2, and Rab25. Each is linked with ANP32A in more than 1 cancer types. Because this analysis shows association rather than direction, both ANP32A-to-partner and partner-to-ANP32A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FoxM1 grouped by ANP32A-low versus ANP32A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANP32A→partner) and Y-score (partner→ANP32A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FoxM1 →	+0.403	+3.000	.007	.037	3	1
UCEC	MSH2 →	-0.326	-3.000	.014	.037	3	1
UCEC	Rab25 →	-0.529	-3.000	.005	.037	3	1
UCEC	Annexin-1 →	+1.325	+2.827	<.001	.035	3	1
UCEC	ATM →	-0.691	-3.000	.008	.037	3	1
UCEC	Caspase-8 →	-0.325	-3.000	.025	.037	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

FoxM1 by ANP32A expression — UCEC

Explore this box plot interactively →