ANP32A

Across TCGA cell cohorts, ANP32A RNA expression is significantly associated with the go_rna of many other GO terms, with 5,315 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ANP32A-associated GO terms across cancer lineages are Protein localization to condensed chromosome, DNA replication checkpoint signaling, and Negative regulation of DNA-templated DNA replication. Each is linked with ANP32A in more than 16 cancer types. Because this analysis shows association rather than direction, both ANP32A-to-partner and partner-to-ANP32A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to condensed chromosome grouped by ANP32A-low versus ANP32A-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ANP32A→partner) and Y-score (partner→ANP32A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Protein localization to condensed chromosome →	+0.173	+0.724	<.001	<.001	3	17
BONE	DNA replication checkpoint signaling →	+0.203	+1.004	.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Negative regulation of DNA-templated DNA replication →	+0.141	+1.121	.001	<.001	3	16
OESOPHAGUS	Protein localization to kinetochore →	+0.153	+0.658	.001	.002	3	16
SOFT_TISSUE	Spindle elongation →	+0.232	+1.018	.001	.002	3	16
SOFT_TISSUE	Nuclear chromosome segregation →	+0.099	+1.222	.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,315 associations by consensus.

Protein localization to condensed chromosome by ANP32A expression — OESOPHAGUS

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