ANO6

Across TCGA patient cohorts, ANO6 protein abundance is significantly associated with the RNA expression of many other genes, with 10,941 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ANO6-associated genes across cancer lineages are RARRES2, HTRA1, and NNMT. Each is linked with ANO6 in more than 5 cancer types. Because this analysis shows association rather than direction, both ANO6-to-partner and partner-to-ANO6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANO6 versus RARRES2 in OV, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANO6→partner) and Y-score (partner→ANO6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RARRES2 →	+1.676	+0.563	<.001	<.001	3	6
BRCA	HTRA1 →	+1.294	+0.487	<.001	<.001	3	6
OV	NNMT →	+2.272	+0.628	<.001	<.001	3	6
OV	CAVIN1 →	+1.241	+0.584	<.001	<.001	3	6
OV	LGALS1 →	+1.285	+0.568	<.001	<.001	3	5
OV	SRPX2 →	+1.582	+0.536	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,941 associations by consensus.

ANO6 vs RARRES2 — OV

Explore this scatter interactively →