ANO5

Across TCGA patient cohorts, ANO5 protein abundance is significantly associated with the RNA expression of many other genes, with 6,464 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ANO5-associated genes across cancer lineages are FCGR3B, CXCR1, and FAM86EP. Each is linked with ANO5 in more than 2 cancer types. Because this analysis shows association rather than direction, both ANO5-to-partner and partner-to-ANO5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANO5 versus FCGR3B in LUAD, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANO5→partner) and Y-score (partner→ANO5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	FCGR3B →	+1.248	+0.745	<.001	<.001	3	3
LSCC	CXCR1 →	+1.036	+0.652	<.001	<.001	3	3
GBM	FAM86EP →	-0.492	-0.675	.002	.006	3	3
GBM	RNF213-AS1 →	-0.666	-0.825	.005	.006	3	3
LUAD	XBP1 →	+0.704	+0.717	<.001	<.001	3	2
LSCC	PARP4 →	-0.482	-0.568	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,464 associations by consensus.

ANO5 vs FCGR3B — LUAD

Explore this scatter interactively →