ANO3

Across TCGA cell cohorts, ANO3 mutation is significantly associated with the RNA expression of many other genes, with 396 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANO3-associated genes across cancer lineages are CCDC172, CBLIF, and C14orf180. Each is linked with ANO3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANO3-to-partner and partner-to-ANO3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC172 grouped by ANO3-low versus ANO3-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANO3→partner) and Y-score (partner→ANO3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	CCDC172 →	+0.052	+5.369	<.001	.004	3	2
LARGE_INTESTINE	CBLIF →	+0.219	+3.005	.006	.002	3	2
LARGE_INTESTINE	C14orf180 →	+0.108	+2.740	<.001	.001	3	2
LARGE_INTESTINE	FAM205A →	+0.016	+2.252	<.001	.005	3	2
LARGE_INTESTINE	SMIM33 →	+0.586	+2.577	<.001	.007	3	2
BLOOD_Leukemia	GLRA2 →	+0.025	+3.376	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 396 associations by consensus.

CCDC172 by ANO3 expression — SOFT_TISSUE

Explore this box plot interactively →