ANO1

Across TCGA patient cohorts, ANO1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,476 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible ANO1-associated proteins across cancer lineages are PPFIBP1, AEBP1, and PDLIM4. Each is linked with ANO1 in more than 5 cancer types. Because this analysis shows association rather than direction, both ANO1-to-partner and partner-to-ANO1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANO1 versus PPFIBP1 in GBM, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ANO1→partner) and Y-score (partner→ANO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PPFIBP1 →	+0.422	+0.794	<.001	<.001	3	6
CCRCC	AEBP1 →	+1.041	+0.953	<.001	<.001	3	6
CCRCC	PDLIM4 →	+1.072	+1.042	<.001	<.001	3	6
HNSC	STARD7 →	-0.228	-1.519	<.001	<.001	3	5
LSCC	AFAP1L2 →	+0.482	+0.974	<.001	<.001	3	5
PDAC	FLNB →	+0.424	+0.793	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,476 associations by consensus.

ANO1 vs PPFIBP1 — GBM

Explore this scatter interactively →