ANKZF1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ANKZF1 mutation is significantly associated with the RNA expression of many other genes, with 4,206 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKZF1-associated genes across cancer lineages are OR7E4P, CNN2P8, and H2BC14. Each is linked with ANKZF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANKZF1-to-partner and partner-to-ANKZF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR7E4P grouped by ANKZF1-low versus ANKZF1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKZF1→partner) and Y-score (partner→ANKZF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCOR7E4P →+0.110+4.705<.001.00332
READCNN2P8 →+0.088+4.142.005.00432
UCECH2BC14 →+0.371+2.102.002<.00132
UCECMB21D2 →-0.612-1.893.003<.00132
UCECRNU6-42P →+0.551+1.867<.001<.00132
UCECRNU6-933P →+0.440+2.272<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,206 associations by consensus.

OR7E4P by ANKZF1 expression — CESC

Box plot of OR7E4P in ANKZF1-low vs ANKZF1-high samples in CESC.

Explore this box plot interactively →

Exploration