ANKS6

Across TCGA patient cohorts, ANKS6 mutation is significantly associated with the RNA expression of many other genes, with 3,374 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANKS6-associated genes across cancer lineages are CCNB2, ZNF367, and PPIP5K1. Each is linked with ANKS6 in more than 3 cancer types. Because this analysis shows association rather than direction, both ANKS6-to-partner and partner-to-ANKS6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCNB2 grouped by ANKS6-low versus ANKS6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANKS6→partner) and Y-score (partner→ANKS6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CCNB2 →	+0.551	+2.345	.006	.003	3	4
UCEC	ZNF367 →	+0.762	+2.201	<.001	<.001	3	4
UCEC	PPIP5K1 →	+0.377	+1.617	<.001	.006	3	4
UCEC	SNRNP40 →	+0.485	+2.906	.004	.001	3	4
STAD	PKM →	+0.955	+3.347	<.001	.004	3	4
UCEC	WDHD1 →	+0.581	+1.895	.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,374 associations by consensus.

CCNB2 by ANKS6 expression — UCEC

Explore this box plot interactively →